abstract：:In the pediatric population, little is known on de novo DSA development, its impact on graft function, and association with suboptimal IS. We assessed the prevalence of de novo DSA in the Vienna cohort of 40 renal transplanted children and adolescents and prospectively followed its association with clinical parameters...

journal_title：Pediatric transplantation

authors： Rusai K,Dworak J,Potemkina A,Fischer G,Csaicsich D,Arbeiter K,Aufricht C,Müller-Sacherer T

更新日期：2016-06-01 00:00:00

abstract：:PV thrombosis following pediatric LT is a serious complication that may lead to graft loss. LDLT poses limitations with regard to the availability of vein grafts for complex PV reconstructions. We herein report a unique reconstruction of the PV inflow in a one-yr-old boy with situs inversus undergoing re-LDLT. The inf...

journal_title：Pediatric transplantation

authors： Uchida H,Fukuda A,Sasaki K,Shigeta T,Hirata Y,Kanazawa H,Mali VP,Miyazaki O,Nosaka S,Sakamoto S,Mureo K

更新日期：2016-06-01 00:00:00

abstract：:Paediatric HR T-cell ALL demonstrates dismal prognosis with chemotherapy, and poor outcomes could be improved with allo-SCT. HID-SCT is an almost immediately available choice; however, few studies have focused on the outcomes of HID-SCT for paediatric HR T-ALL. Forty-eight consecutive HR T-ALL children who underwent H...

journal_title：Pediatric transplantation

authors： Xu ZL,Huang XJ,Liu KY,Chen H,Zhang XH,Han W,Chen YH,Wang FR,Wang JZ,Wang Y,Chen Y,Yan CH,Xu LP

更新日期：2016-06-01 00:00:00

abstract：:Intra-operative arterial vasospasm during pediatric renal transplantation is an urgent clinical situation resulting in end-organ ischemia, associated changes in parenchymal turgor and color, diminished flow on ultrasound, and if left untreated, allograft loss. We hypothesized that intra-operative intra-arterial inject...

journal_title：Pediatric transplantation

authors： Penna FJ,Harvey E,John P,Armstrong D,Luginbuehl I,Odeh RI,Alyami F,Koyle MA,Lorenzo AJ

更新日期：2016-05-01 00:00:00

abstract：:Comparisons of perceived barriers to adherence in pediatric and adolescent SOT have not been systematically conducted despite association between medication non-adherence and poor outcome. Fifteen centers in CTOT-C enrolled patients in a cross-sectional study. Subjects' guardians completed the PMBS and subjects over e...

journal_title：Pediatric transplantation

authors： Danziger-Isakov L,Frazier TW,Worley S,Williams N,Shellmer D,Dharnidharka VR,Gupta NA,Ikle D,Sweet SC,CTOTC-05 Consortium.

更新日期：2016-03-01 00:00:00

abstract：:Although de novo DSA are associated with inferior graft survival, there are no effective strategies to prevent their formation. Underexposure to MPA (prodrug: MMF) also contributes to rejection rates early after transplantation, but the effect of this phenomenon on the formation of DSA long-term post-transplantation i...

journal_title：Pediatric transplantation

authors： Filler G,Todorova EK,Bax K,Alvarez-Elías AC,Huang SH,Kobrzynski MC

更新日期：2016-02-01 00:00:00

abstract：:FA is an autosomal recessive disorder characterized by small stature and renal abnormalities. FA can lead to progressive bone marrow failure, myelodysplastic syndrome, or acute leukemia. Using a multidisciplinary team approach, we managed a 3-yr-old boy with FA who simultaneously developed renal and hematopoietic fail...

journal_title：Pediatric transplantation

authors： Vincent CL,Primack WA,Hipps J,Kasow KA

更新日期：2016-02-01 00:00:00

abstract：:The clinical significance and prognostic impact of IRFR in pediatric recipients of haploidentical SCT are not clearly understood. Therefore, we attempted to determine how IRFR affects clinical outcomes in children. Clinical data from 100 consecutive pediatric patients (60 boys and 40 girls; median age, 12 yr [range, 2...

journal_title：Pediatric transplantation

authors： Chen Y,Huang XJ,Liu KY,Chen H,Chen YH,Zhang XH,Wang FR,Han W,Wang JZ,Wang Y,Yan CH,Zhang YY,Sun YQ,Xu LP

更新日期：2015-12-01 00:00:00

abstract：:PTLD is a serious complication of both solid organ and BMT. This study assessed whether (18) F-FDG PET, when added to CT scan, had additional value in the initial evaluation of PTLD in pediatric patients and whether PET/CT at baseline can reliably guide biopsy. This retrospective study evaluated 34 consecutive pediatr...

journal_title：Pediatric transplantation

authors： Vali R,Punnett A,Bajno L,Moineddin R,Shammas A

更新日期：2015-12-01 00:00:00

abstract：:Dysregulation of genes involved in the cell cycle such as TP53, P21, P16, and PTEN plays a key role in oncogenesis. We have earlier reported increased expression of the TP53 encoded protein p53, in bone marrow samples from pediatric patients with more aggressive, rare chronic myeloid malignancies. The aim of this stud...

journal_title：Pediatric transplantation

authors： Mattsson K,Honkaniemi E,Barbany G,Gustafsson B

更新日期：2015-11-01 00:00:00

abstract：:DD kidney allocation protocols may influence timing of transplantation and graft quality for pediatric recipients. This study aimed to evaluate the effects of these protocols, including pediatric priority, on waiting time on dialysis, transplant type, donor age, and HLA matching according to state of transplant in Aus...

journal_title：Pediatric transplantation

authors： Le Page AK,Johnstone LM,Kennedy SE

更新日期：2015-09-01 00:00:00

abstract：:A standard treatment is yet to be established for steroid-refractory acute aGVHD following HSCT. The effects of MMF have not been well studied in children with aGVHD. We evaluated the effectiveness of oral MMF in 14 children with steroid-refractory aGVHD (grade II in one patient, grade III to IV in 13 patients). The m...

journal_title：Pediatric transplantation

authors： Inagaki J,Kodama Y,Fukano R,Noguchi M,Okamura J

更新日期：2015-09-01 00:00:00

abstract：UNLABELLED:aHUS is a clinical challenge for successful renal transplantation. CASE REPORT:A 14-yr-old girl lost her kidneys at the age of 7, due to CFH antibodies and CFH-related protein (CFHR1/CFHR3) homozygous deletion-associated aHUS. CFH, CFI, and MCP gene mutations were excluded. The patient was a candidate for r...

journal_title：Pediatric transplantation

authors： Grenda R,Jarmużek W,Rubik J,Prokurat S,Miklaszewska M,Drozdz D,Zachwieja K,Ardissino G,Hofer J

更新日期：2015-09-01 00:00:00

abstract：:Chronic rejection is the leading cause of graft loss following pediatric kidney transplantation. Our group and others have demonstrated an association between the development of Abs to self-antigens and chronic rejection following adult lung and heart transplantation. The goal of this study was to determine whether Ab...

journal_title：Pediatric transplantation

authors： Hesemann LE,Subramanian V,Mohanakumar T,Dharnidharka VR

更新日期：2015-08-01 00:00:00

abstract：:LDLT is a well-established treatment for most terminal liver diseases in children. Survival rates have improved, yet few studies have considered HRQoL or sleep problems in LDLT recipients. In this cross-sectional study, we enrolled 51 children who had undergone LDLT in Renji Hospital. PedsQL(™) 4.0 Generic Core Scales...

journal_title：Pediatric transplantation

authors： He K,Shen C,Chen X,Han L,Xi Z,Zhou T,Zhang J,Xia Q

更新日期：2015-08-01 00:00:00

abstract：UNLABELLED:Liver transplantation treats the hepatic affectation of UCDs; however, irreversible neurologic damage pretransplant is difficult to assess providing transplant teams with ethical dilemmas for liver transplantation. The purpose of our study was to determine whether pretransplant neuroimaging can predict devel...

journal_title：Pediatric transplantation

authors： Bolton SM,Campbell KM,Kukreja M,Kohli R

更新日期：2015-08-01 00:00:00

abstract：:Approximately 800 pediatric renal transplants are performed annually in the United States. VUR or obstruction may cause graft failure requiring redo ureteroneocystostomy. We examined possible risk factors and cost using the PHIS national database. We examined the PHIS for 8.5 yr to determine the association between re...

journal_title：Pediatric transplantation

authors： Godebu E,Palazzi K,Bush R,Marietti S,Chiang G

更新日期：2015-08-01 00:00:00

abstract：:T1D is an autoimmune disease, which may be caused by lack of insulin-secreting β cells due to damage of autoimmune system. Living with T1D is a challenge for the child and the family; cell transplantation is a treatment option for diabetes in children. To establish a microenvironment suitable for cell growth and proli...

journal_title：Pediatric transplantation

authors： Yuan X,Huang Y,Guo Y,Wang L,Guo Q,Xu T,Wu D,Zhou P,Zhu S,Wang Y,Fan X,Zhu M,Lu Y,Wang Z

更新日期：2015-06-01 00:00:00

abstract：:HSCT has substantially improved pediatric acquired SAA patients' outcomes. Retrospectively, we attempted to assess the outcome of MRD HSCT in 65 pediatric patients referred to a single center from 1992 to 2012. We were particularly interested to find out whether source of SC (PB, n = 40 and BM, n = 25) significantly i...

journal_title：Pediatric transplantation

authors： Hamidieh AA,Mozafari M,Noshad S,Alimoghaddam K,Behfar M,Ghavamzadeh A

更新日期：2015-06-01 00:00:00

abstract：:BM remains an important source of stem cells. The BM characteristics change with age but the estimation of CD34 calculation of one CD34+ cell per 100 nucleated cells is used for all donors including pediatric donors in the operating room before getting the actual CD34 count. In order to see whether this formula is app...

journal_title：Pediatric transplantation

authors： Ince EU,Ileri T,Dogu F,Ates C,Cakmakli H,Dalva K,Ikinciogullari A,Uysal Z,Ertem M

更新日期：2015-06-01 00:00:00

abstract：:HSCT-associated thrombotic microangiopathy (TA-TMA) is a severe complication with a poor prognosis. Recently, it has been reported that complement system dysregulation, such as CFH autoantibodies and deletions CFH-related genes 3 and 1, induced TA-TMA. In addition, C4d-positive renal arterioles are both a good marker ...

journal_title：Pediatric transplantation

authors： Sakamoto K,Imamura T,Osone S,Nishimura A,Nishida M,Ishida H,Hosoi H

更新日期：2015-06-01 00:00:00

abstract：:This study aims to evaluate BMD and bone biomarkers and to investigate the effects of immunosuppressives on bone disease after RTx. Thirty-three RTR aged 16.7 ± 3.7 yr and healthy controls (n = 32) were enrolled. There was no difference between pre-RTx BMD and BMD at the time of study (45.9 ± 30.9 months after RTx), w...

journal_title：Pediatric transplantation

authors： Büyükkaragöz B,Bakkaloglu SA,Kandur Y,Isiyel E,Akcaboy M,Buyan N,Hasanoglu E

更新日期：2015-06-01 00:00:00

abstract：:OM is a painful inflammatory condition of the oral mucosa, derived from the toxic effects of chemotherapy and radiotherapy. High OM severity is frequently present in HSCT pediatric patients, who exhibit multiple painful ulcers that limit their mastication and swallowing, leading to poor nutritional status. Few studies...

journal_title：Pediatric transplantation

authors： Eduardo Fde P,Bezinelli LM,de Carvalho DL,Lopes RM,Fernandes JF,Brumatti M,Vince CS,de Azambuja AM,Vogel C,Hamerschlak N,Correa L

更新日期：2015-05-01 00:00:00

abstract：:Acute graft-versus-host disease (GVHD) is a common and serious complication of allogeneic blood and marrow transplantation. Acute GVHD is commonly graded according to modified Glucksberg criteria. There is considerable within-grade heterogeneity with different patterns of skin, liver, or gut involvement. In this comme...

journal_title：Pediatric transplantation

authors： Goyal RK,Goyal M,Sankaranarayan K

更新日期：2015-05-01 00:00:00

abstract：:NH is the most common identifiable cause of ALF in the neonate. LT is the definitive treatment for neonates with NH who have failed medical therapy. Our aim was to determine the outcomes of LT in infants with NH. Patients (less than one yr of age) with NH who were listed for LT and patients who underwent LT between 19...

journal_title：Pediatric transplantation

authors： Sheflin-Findling S,Annunziato RA,Chu J,Arvelakis A,Mahon D,Arnon R

更新日期：2015-03-01 00:00:00

abstract：:The aim of this study is to correlate the US, laboratory, and cholangiography findings in pediatric liver transplant patients with biliary complications, trying to identify reliable decision-making tools for the management of these complications. Retrospective review was carried out of US results in 39 consecutive pat...

journal_title：Pediatric transplantation

authors： Teplisky D,Urueña Tincani E,Halac E,Garriga M,Cervio G,Imventarza O,Sierre S

更新日期：2015-03-01 00:00:00

abstract：:We present the unique case of a pediatric patient who received chemotherapy for a diagnosis of CD, while mechanically supported with a Berlin EXCOR LVAD secondary to restrictive cardiomyopathy. A four-yr-old previously healthy male with restrictive cardiomyopathy required MCS after cardiac arrest but was diagnosed wit...

journal_title：Pediatric transplantation

authors： Thomas TO,Chandrakasan S,O'Brien M,Jefferies JL,Ryan TD,Wilmot I,Baker ML,Madueme PC,Morales D,Lorts A

更新日期：2015-02-01 00:00:00

abstract：:We report a case of EBV encephalitis in a seven-yr-old child with Ph+ ALL. Two months after an allogeneic HSCT from his HLA mismatched mother, the patient showed an altered sensorium, generalized seizures, and a left hemiparesis. Brain MRI demonstrated multiple lesions highly suggestive for viral encephalitis. Blood a...

journal_title：Pediatric transplantation

authors： Barberi W,Perrone S,Iori AP,Torelli GF,Testi AM,Moleti ML,Ceglie T,Papoff P,Caresta E,Antonelli M,Gianno F,Melone A,Badiali M,Giangaspero F,Foà R,Gentile G

更新日期：2015-02-01 00:00:00

abstract：:Bacillus cereus is a spore-forming, gram-positive bacterium that causes food poisoning presenting with either emesis or diarrhea. Diarrhea is caused by proteinaceous enterotoxin complexes, mainly hemolysin BL, non-hemolytic enterotoxin (NHE), and cytotoxin K. In contrast, emesis is caused by the ingestion of the depsi...

journal_title：Pediatric transplantation

authors： Tschiedel E,Rath PM,Steinmann J,Becker H,Dietrich R,Paul A,Felderhoff-Müser U,Dohna-Schwake C

更新日期：2015-02-01 00:00:00

abstract：:LI is a subset of the heterotaxy syndrome and a rare birth defect that involves the heart and other organs. It can be combined with extracardiac abnormalities, especially BA. CHD can be associated with LI in up to 15% of cases, although it is rare in BA. Pediatric LT for a child with ESLD due to BA combined with LI an...

journal_title：Pediatric transplantation

authors： Youn JK,Lee JM,Yi NJ,Choi YR,Suh SW,You T,Lee KW,Jung CW,Lee JW,Bae EJ,Ko JS,Kim WH,Park KW,Suh KS

更新日期：2014-12-01 00:00:00

abstract：:To analyze the clinical profile and outcome of pediatric patients who had undergone a liver and/or RT at our center over a five yr period, case records of all the patients who had undergone a liver or RT were analyzed retrospectively. One hundred solid organ transplants were performed at our center between January 200...

journal_title：Pediatric transplantation

authors： Sibal A,Malhotra S,Guru FR,Bhatia V,Kapoor A,Seth S,Jerath N,Jasuja S,Rajkumari V,Wadhawan M,Aggarwal DK,Guleria S,Shrivastava RN,Gupta S

更新日期：2014-11-01 00:00:00

abstract：:Transplantation is the accepted mode of treatment for patients with end-stage organ disease affecting the heart, lungs, kidney, pancreas, liver and intestine. Long-term outcomes have significantly improved and the aim of management is no longer only long-term survival, but also focuses on quality of life especially in...

journal_title：Pediatric transplantation

authors： Spearman CW,McCulloch MI

更新日期：2014-11-01 00:00:00

abstract：:To describe the prevalence and outcomes of renal transplantation in children with ID we performed a retrospective cohort analysis of all children receiving a first kidney-alone transplant in the UNOS dataset from 2008 to 2011. Recipients with definite, probable, and without ID were compared using chi-square tests. Kap...

journal_title：Pediatric transplantation

authors： Wightman A,Young B,Bradford M,Dick A,Healey P,McDonald R,Smith J

更新日期：2014-11-01 00:00:00

abstract：:The prospective cross-sectional study investigated the 6MWT performance in pediatric group of liver transplant recipients (6-17 yr, median post-transplantation time of 22 months) and compared to the normal values obtained in healthy children as well as evaluated the reproducibility of the 6MWT. We analyzed the relatio...

journal_title：Pediatric transplantation

authors： Maria da Silva R,Brunow de Carvalho W,Johnston C,Borba de Castro M,Manta Ferreira I,Patti CL,Anthero de Azevedo R,Miziara Gonzalez A,Moura Linhares M,Augusto Salzedas-Netto A

更新日期：2014-09-01 00:00:00

abstract：:HSCT is associated with a high risk of late morbidity. The aim of this study was to evaluate the frequency, time frame, risk factors, and possible etiology of pulmonary dysfunction following allogeneic HSCT in childhood. We evaluated the pulmonary function of 51 HSCT patients (>6 yr), by including FVC and FEV1 values ...

journal_title：Pediatric transplantation

authors： Madanat-Harjuoja LM,Valjento S,Vettenranta K,Kajosaari M,Dyba T,Taskinen M

更新日期：2014-09-01 00:00:00

abstract：:For infants with SCID, the ideal conditioning regimen before allogeneic HCT would omit cytotoxic chemotherapy to minimize short- and long-term complications. We performed a prospective pilot trial with G-CSF plus plerixafor given to the host to mobilize HSC from their niches. We enrolled six patients who received CD34...

journal_title：Pediatric transplantation

authors： Dvorak CC,Horn BN,Puck JM,Czechowicz A,Shizuru JA,Ko RM,Cowan MJ

更新日期：2014-09-01 00:00:00

abstract：:Vitamin C deficiency in developed countries is typically observed in patients with unique clinical conditions such as cystic fibrosis or anorexia nervosa, or in patients on long-term tube feeds. We report here a clinical observation in six pediatric and adolescent patients (median age 17.5 yr, range 9.8-23.5 yr) with ...

journal_title：Pediatric transplantation

authors： Kletzel M,Powers K,Hayes M

更新日期：2014-08-01 00:00:00

abstract：:The waiting period for an organ transplant has been described as a time of tremendous uncertainty and vulnerability, posing unique challenges and stressors for pediatric transplant candidates and their families. It has been identified as the most stressful stage of the transplant journey, yet little attention has been...

journal_title：Pediatric transplantation

authors： Anthony SJ,Annunziato RA,Fairey E,Kelly VL,So S,Wray J

更新日期：2014-08-01 00:00:00

abstract：:Management of late humoral rejection remains challenging, and DSA may persist. A case report illustrates how individual DSA titers using solid-phase-based assays may help to assess for accommodation. A male cystinosis patient received a cadaveric renal transplant at the age of 12 yr with a daclizumab, tacrolimus, MMF,...

journal_title：Pediatric transplantation

authors： Filler G,Grimmer J,Ball E,Sharma AP,Huang SH

更新日期：2014-06-01 00:00:00

abstract：:Effective antibody removal using PE, DFPP and IA has led to increased access to live donor organs through ABOi RT for patients with chronic kidney disease. However, there have been no head-to-head comparator studies between these modalities, and the choice of technique is usually influenced by cost and institutional p...

journal_title：Pediatric transplantation

authors： Thalgahagoda S,Webb NJ,Roberts D,Birch A,Milford DV,Tavakoli A,Shenoy M

更新日期：2014-05-01 00:00:00